CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13938
Family Name Beta-2 adrenergic receptor and Beta-3 adrenergic receptor ligand SureCN6333781 family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00364984 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Pristinamycin family 2 2
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 2-benzyl-6-... 9 80
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 1 3
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 3
Cathepsin S and Cathepsin K inhibitor N-[(2S)-3-(1-methylcyclo... 2 0
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Cytochrome P450 2C19 and Inositol monophosphatase 1 inhibitor ... 1 0
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[6-propan-2-ylo... 1 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 4
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 8 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
RAC-alpha serine/threonine-protein kinase inhibitor Isoquinoli... 1 0
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
Protein kinase C theta type and Protein kinase C delta type in... 5 4
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Metabotropic glutamate receptor 5 ligand 3-fluoro-5-(5-pyridin... 1 0
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45262 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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