CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13942
Family Name Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4-methoxyquinolin-2-yl)-3-N-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00425256 Functional Category Bioactive
Superfamily Aurora kinase A and Prelamin-A/C Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Platelet-der... 6 8
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Dual specificity protein kinase CLK4 and Dual specificity tyro... 1 14
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Corticotropin-releasing factor receptor 1 ligand 6-ethyl-3-met... 6 10
Mu-type opioid receptor and Nitric oxide synthase, brain ligan... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Melanin-concentrating hormone receptor 1 ligand SureCN5431614 ... 1 2
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 0
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 7-methy... 2 0
Glucokinase inhibitor AGN-PC-03ZE4O family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425258 CHEMBL250516 Bioactive (1S,3S)-1-N-(7-methoxy-4-methylquinolin-2-yl)-3-N-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
CFAMM00425256 CHEMBL249489 Bioactive (1S,3S)-1-N-(4-methoxyquinolin-2-yl)-3-N-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
CFAMM00425255 CHEMBL400883 Bioactive (1S,3S)-1-N-(6-methoxy-4-methylquinolin-2-yl)-3-N-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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