CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13946
Family Name Somatostatin receptor type 1 and Somatostatin receptor type 2 ligand 2-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]-6-fluorobenzonitrile family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00425274 Functional Category Bioactive
Superfamily Somatostatin receptor type 1 and Somatostatin receptor type 2 Binder Superfamily 3
Class Class 2276

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Mu-type opioid receptor Ligand Cyprodime Family 12 8
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethyl... 1 4
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Somatostatin receptor type 1 and D(4) dopamine receptor ligand... 9 10
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 2
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 1 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425274 CHEMBL400136 Bioactive 2-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]-6-fluorobenzonitrile
CFAMM00425272 CHEMBL400907 Bioactive [(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-3-yl]-[4-(4-fluorophenyl)piperazin-1-yl]methanone
CFAMM00425271 CHEMBL249723 Bioactive [(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-3-yl]-[4-(3-fluorophenyl)piperazin-1-yl]methanone
CFAMM00425270 CHEMBL250522 Bioactive 8-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]naphthalene-2-carbonitrile
CFAMM00425276 CHEMBL249932 Bioactive 4-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]benzonitrile
CFAMM00425269 CHEMBL250304 Bioactive [(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-3-yl]-[4-(3,4-difluorophenyl)piperazin-1-yl]methanone
CFAMM00425275 CHEMBL249930 Bioactive 2-[4-[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline-3-carbonyl]piperazin-1-yl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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