CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13954
Family Name Cysteine protease and Cruzipain inhibitor ethyl (2S,3R)-3-[(2S)-4-phenyl-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoyl]oxirane-2-carboxylate family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00425307 Functional Category Bioactive
Superfamily Cysteine protease and Cruzipain inhibitor ethyl (2S,3R)-3-[(2S)-4-phenyl-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoyl]oxirane-2-carboxylate Superfamily
Class Class 1842

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cruzipain Inhibitor WRR-204 Family 18 35
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Caspase-1 inhibitor (3S)-5-(3,3-diphenylpropanoyloxy)-3-[[(2S)... 3 6
Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 3 1
Pol polyprotein inhibitor AC1LADQG family 7 1
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
Cathepsin B inhibitor AC1LD7MA family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425307 CHEMBL249814 Bioactive ethyl (2S,3R)-3-[(2S)-4-phenyl-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoyl]oxirane-2-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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