CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13967
Family Name Kinesin-like protein KIF11 and Potassium voltage-gated channel subfamily H member 2 ligand 1-[(3R,3aR)-3-[3-(dimethylamino)propyl]-8-fluoro-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00425382 Functional Category Bioactive
Superfamily Kinesin-like protein KIF11 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 217

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor Ligand RWJ-68141 Family 5 4
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 2 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 3 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425382 CHEMBL250328 Bioactive 1-[(3R,3aR)-3-[3-(dimethylamino)propyl]-8-fluoro-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone
CFAMM00425388 CHEMBL250127 Bioactive 1-[(3R,3aR)-3-(3-aminopropyl)-8-fluoro-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone
CFAMM00425387 CHEMBL401476 Bioactive 1-[(3R,3aR)-8-fluoro-3-phenyl-3-(3-piperazin-1-ylpropyl)-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone
CFAMM00425393 CHEMBL251142 Bioactive 1-[3-[(3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-3-yl]propyl]-4-methyl-1,4-diazepan-5-one
CFAMM00425386 CHEMBL250125 Bioactive dihydropyrazolobenzoxazine, 1
CFAMM00425392 CHEMBL399378 Bioactive 1-[(3R,3aR)-8-methyl-3-(3-morpholin-4-ylpropyl)-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone
CFAMM00425391 CHEMBL250743 Bioactive SureCN13178362
CFAMM00425390 CHEMBL438876 Bioactive 1-[3-[(3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-3-yl]propyl]-1,4-diazepan-5-one
CFAMM00425383 CHEMBL398478 Bioactive 1-[(3R,3aR)-8-fluoro-3-(3-morpholin-4-ylpropyl)-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone
CFAMM00425389 CHEMBL250532 Bioactive 1-[(3R,3aR)-3-[3-(dimethylamino)propyl]-8-methyl-3-phenyl-3a,4-dihydropyrazolo[5,1-c][1,4]benzoxazin-2-yl]ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543