CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13974
Family Name Prothrombin inhibitor 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00425432 Functional Category Bioactive
Superfamily Prothrombin and Prelamin-A/C Binder Superfamily 10
Class Class 3069

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Prothrombin inhibitor SureCN6057665 family 2 0
Prothrombin inhibitor 2-[6-cyano-3-[[2,2-difluoro-2-(3-methylp... 10 0


External ID

Functional Category

Molecule Name

CFAMM00425427 CHEMBL250650 Bioactive 2-[6-chloro-3-[[2-(5-chloropyridin-2-yl)-2,2-difluoroethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00425432 CHEMBL250463 Bioactive 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00425431 CHEMBL250273 Bioactive 2-[6-chloro-3-[(2,2-difluoro-2-quinolin-8-ylethyl)amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00425430 CHEMBL250460 Bioactive 2-[6-chloro-3-[(2,2-difluoro-2-isoquinolin-5-ylethyl)amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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