CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13975
Family Name Beta-secretase 1 inhibitor CHEMBL400438 family
No. of Seeds 5 No. of Other Members 16
Family Centroid CFAMM00425442 Functional Category Bioactive
Superfamily Trypsin-1 and Beta-secretase 1 Binder Superfamily
Class Class 2096

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
Intedanib family 7 54
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Beta-secretase 1 Inhibitor KMI-538 Family 4 20
Beta-secretase 1 Inhibitor GSK-188909 Family 16 11
Beta-secretase 1 and Cathepsin D inhibitor 3ixk family 2 9
Beta-secretase 1 and Cathepsin D inhibitor 3ixj family 10 21
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 5 2
Cathepsin B inhibitor 3-[[(2R)-2-cyano-2-[[(2S)-3-(3-methylphe... 6 8
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
Cathepsin D and Cathepsin E inhibitor methyl (2S)-1-[(2R)-2-[[... 1 0
Beta-secretase 1 and Beta-secretase 2 inhibitor 3-(1,1-dioxoth... 6 2
Cathepsin B and Cathepsin L1 inhibitor 5-[[(2R)-2-[[(2S)-2-ani... 1 0
Cathepsin B and Cathepsin L1 inhibitor SureCN14345745 family 2 0
Beta-secretase 1 inhibitor N-[(2S,3R)-1-(3,5-difluorophenyl)-3... 5 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 0
Cathepsin B inhibitor 3-[[(2R)-2-cyano-2-[[(2S)-3-(3-methylphe... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425442 CHEMBL400438 Bioactive CHEMBL400438
CFAMM00425440 CHEMBL400530 Bioactive CHEMBL400530
CFAMM00425453 CHEMBL250295 Bioactive CHEMBL250295
CFAMM00425446 CHEMBL427884 Bioactive CHEMBL427884
CFAMM00425444 CHEMBL429666 Bioactive CHEMBL429666

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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