CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13997
Family Name Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor 5-[[4-[3-(2,4,5-trichlorophenoxy)propoxy]phenyl]methyl]pyrimidine-2,4-diamine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00425537 Functional Category Bioactive
Superfamily Proto-oncogene tyrosine-protein kinase receptor Ret and Bifunctional dihydrofolate reductase-thymidylate synthase Binder Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
SB1518 family 7 103
Deoxycytidine kinase inhibitor AGN-PC-07Z9C8 family 5 3
Deoxycytidine kinase inhibitor AGN-PC-07Z9GO family 10 2
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425537 CHEMBL25112 Bioactive 5-[[4-[3-(2,4,5-trichlorophenoxy)propoxy]phenyl]methyl]pyrimidine-2,4-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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