CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM13998
Family Name Transient receptor potential cation channel subfamily V member 1 ligand 1-[6-fluoro-1-(thiophen-2-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-3-isoquinolin-5-ylurea family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00425538 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and C-C chemokine receptor type 3 Binder Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 158
Amg 423 family 7 47
Aurora kinase A Inhibitor ABT-348 Family 20 49
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
5-hydroxytryptamine receptor Ligand Sl65.0472 Family 2 16
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
Prostaglandin E synthase inhibitor AGN-PC-09QHBK family 3 1
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Vascular endothelial growth factor receptor 2 and Platelet-der... 3 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 5 0
Protein-cysteine N-palmitoyltransferase porcupine inhibitor 2-... 5 2
Vascular endothelial growth factor receptor 2 ligand Thienopyr... 2 2
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(4-py... 9 0


External ID

Functional Category

Molecule Name

CFAMM00425538 CHEMBL251181 Bioactive 1-[6-fluoro-1-(thiophen-2-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-3-isoquinolin-5-ylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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