CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1400
Family Name Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhibitor (E)-N-(2-chlorophenyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00323019 Functional Category Bioactive with Natural Product
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 2
Class Class 3359

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Muscarinic acetylcholine receptor M1 and Prelamin-A/C ligand n... 1 7
Amyloid beta A4 protein inhibitor SureCN6372684 family 2 7
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor (E)-2... 2 1
Calcium-activated potassium channel subunit alpha-1 ligand 5-c... 1 2
Metabotropic glutamate receptor 5 ligand CPPHA family 1 0
Nuclear receptor ROR-gamma and Receptor-type tyrosine-protein ... 1 2
4-acetamido-2-[3-(4-chlorophenyl)-3-hydroxyprop-2-enoyl]phenol... 1 1


External ID

Functional Category

Molecule Name

CFAMM00323019 CHEMBL1163867 Bioactive (E)-N-(2-chlorophenyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
CFAMM00323016 CHEMBL1165150 Bioactive (E)-N-(4-chlorophenyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
CFAMM00323015 CHEMBL2336351 Bioactive (E)-N-(4-chlorophenyl)-3-(4-hydroxyphenyl)prop-2-enamide
CFAMM00323014 CHEMBL2336350 Bioactive (E)-N-(2-chlorophenyl)-3-(4-hydroxyphenyl)prop-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



72942 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543