CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14014
Family Name Stromelysin-1 and 72 kDa type IV collagenase inhibitor 2-[4-[4-(3-ethoxyphenyl)-3-methylphenyl]piperidin-1-yl]sulfonyl-N-hydroxy-2-methylpropanamide family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00425660 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Stromelysin-1 Binder Superfamily
Class Class 2524

Cousin Family NamesSeedsMembers
Macrophage metalloelastase and Collagenase 3 inhibitor N-hydro... 2 3
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-N-... 2 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor N-hydro... 3 0


External ID

Functional Category

Molecule Name

CFAMM00425658 CHEMBL398641 Bioactive N-hydroxy-2-[4-[4-[3-(2-hydroxyethoxy)phenyl]-3-methylphenyl]piperidin-1-yl]sulfonyl-2-methylpropanamide
CFAMM00425651 CHEMBL400083 Bioactive N-hydroxy-2-methyl-2-[4-[3-methyl-4-[3-[2-(methylamino)ethoxy]phenyl]phenyl]piperidin-1-yl]sulfonylpropanamide
CFAMM00425655 CHEMBL252117 Bioactive 2-[4-[4-[3-[2-(dimethylamino)ethoxy]phenyl]-3-methylphenyl]piperidin-1-yl]sulfonyl-N-hydroxy-2-methylpropanamide
CFAMM00425654 CHEMBL251916 Bioactive N-hydroxy-2-[4-[4-[3-(2-methoxyethoxy)phenyl]-3-methylphenyl]piperidin-1-yl]sulfonyl-2-methylpropanamide
CFAMM00425660 CHEMBL442445 Bioactive 2-[4-[4-(3-ethoxyphenyl)-3-methylphenyl]piperidin-1-yl]sulfonyl-N-hydroxy-2-methylpropanamide
CFAMM00425653 CHEMBL251918 Bioactive 2-[4-[4-[3-(2-aminoethoxy)phenyl]-3-methylphenyl]piperidin-1-yl]sulfonyl-N-hydroxy-2-methylpropanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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