CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14028
Family Name Macrophage colony-stimulating factor 1 receptor ligand SureCN13405640 family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00425757 Functional Category Bioactive
Superfamily Macrophage colony-stimulating factor 1 receptor and Menin Binder Superfamily
Class Class 2780

Cousin Family NamesSeedsMembers
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 1 0


External ID

Functional Category

Molecule Name

CFAMM00425758 CHEMBL398509 Bioactive 5-Cyano-N-[4-(4-Methylpiperazin-1-Yl)-2-Piperidin-1-Ylphenyl]furan-2-Carboxamide
CFAMM00425757 CHEMBL252436 Bioactive SureCN13405640
CFAMM00425756 CHEMBL252822 Bioactive SureCN13405634
CFAMM00425755 CHEMBL254910 Bioactive AGN-PC-00CSYD
CFAMM00425753 CHEMBL252633 Bioactive 5-cyano-N-[2-(3-fluoropiperidin-1-yl)-4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CFAMM00425752 CHEMBL398237 Bioactive AGN-PC-00E3RX

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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