CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14037
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor (3R)-3-[[4-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperidin-1-yl]methyl]-1,2,3,4-tetrahydroisoquinoline family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00237431 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Binder Superfamily 3
Class Class 100

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Clemastine Family 5 76
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Substance-P receptor Ligand SCH-388714 Family 26 8
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Muscarinic acetylcholine receptor M1 and Sodium-dependent dopa... 2 13
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 1 2
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Substance-P receptor ligand (2S)-3-[[3,5-bis(trifluoromethyl)p... 1 4
Substance-P receptor ligand 4-[[3,5-bis(trifluoromethyl)phenyl... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sigma non-opioid intracellular receptor 1 ligand N-benzyl-2-[(... 1 5
Sodium-dependent dopamine transporter and Transporter inhibito... 1 6
Melanin-concentrating hormone receptor 1 and Alpha-1A adrenerg... 4 6
Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-p... 3 0
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Substance-P receptor ligand SureCN8415737 family 3 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
C-C chemokine receptor type 5 ligand AC1LAKN8 family 4 5
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Sodium-dependent dopamine transporter and Transporter inhibito... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0793IB... 2 0
Sodium-dependent dopamine transporter inhibitor 2-(4-nitrophen... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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