CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14048
Family Name 72 kDa type IV collagenase and Disintegrin and metalloproteinase domain-containing protein 10 inhibitor (6S,7S)-6-[4-(4-cyano-3-methylphenyl)piperazine-1-carbonyl]-N-hydroxy-5-azaspiro[2.5]octane-7-carboxamide family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00425879 Functional Category Bioactive
Superfamily Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glutamamide Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Cathepsin K and Cathepsin B inhibitor AGN-PC-01Z23J family 2 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(cyanomethyl)-... 1 6
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425879 CHEMBL252912 Bioactive (6S,7S)-6-[4-(4-cyano-3-methylphenyl)piperazine-1-carbonyl]-N-hydroxy-5-azaspiro[2.5]octane-7-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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