CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14053
Family Name Coagulation factor X inhibitor 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]ethanone family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00425904 Functional Category Bioactive
Superfamily Coagulation factor X and Prothrombin Inhibitor BMS-740808 Superfamily
Class Class 2345

Cousin Family NamesSeedsMembers
Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family 64 8
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 4 0
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X inhibitor AGN-PC-046RMH family 5 0
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 9 0
Coagulation factor X inhibitor 1-(3-amino-1,2-benzoxazol-5-yl)... 3 0
Coagulation factor X inhibitor SureCN5107814 family 6 0
Coagulation factor X inhibitor SureCN6603523 family 4 0


External ID

Functional Category

Molecule Name

CFAMM00425904 CHEMBL403196 Bioactive 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]ethanone
CFAMM00425903 CHEMBL253297 Bioactive 2-[4-[2-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-oxoethyl]-3-fluorophenyl]benzenesulfonamide
CFAMM00425902 CHEMBL253713 Bioactive 2-[4-[1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-1-oxopropan-2-yl]-3-fluorophenyl]benzenesulfonamide
CFAMM00425901 CHEMBL269191 Bioactive 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]propan-1-one
CFAMM00425900 CHEMBL253094 Bioactive 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[4-(2-methylsulfonylphenyl)phenyl]ethanone
CFAMM00425899 CHEMBL404061 Bioactive 2-[4-[2-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-oxoethyl]phenyl]benzenesulfonamide
CFAMM00425905 CHEMBL253298 Bioactive 1-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-[4-(2-methylsulfonylphenyl)phenyl]propan-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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