CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14056
Family Name Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhibitor (2S)-N-hydroxy-3-[4-(4-methylphenoxy)-N-methylsulfonylanilino]-2-(pyridin-4-ylmethylamino)propanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00425919 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Matrix metalloproteinase-9 Binder Superfamily
Class Class 2449

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Disintegrin and metalloproteinase domain-containing protein 17... 1 3
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 1 3
Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-met... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425919 CHEMBL253242 Bioactive (2S)-N-hydroxy-3-[4-(4-methylphenoxy)-N-methylsulfonylanilino]-2-(pyridin-4-ylmethylamino)propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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