CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14065
Family Name 72 kDa type IV collagenase and Neutrophil collagenase inhibitor SureCN7250053 family
No. of Seeds 12 No. of Other Members 20
Family Centroid CFAMM00392712 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Collagenase 3 Binder Superfamily
Class Class 3090

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Trypsin Inhibitor Benzamidrazone Analogue Family 2 6 38
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 45
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 8
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Collagenase 3 and 72 kDa type IV collagenase inhibitor SureCN1... 8 50
Collagenase 3 and A disintegrin and metalloproteinase with thr... 10 19
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-[(6R)... 1 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 1
Kinesin-like protein KIF11 inhibitor 2-amino-5-(4-methoxypheny... 1 4
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 6
Collagenase 3 inhibitor (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-... 34 1
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 2 0
Prothrombin inhibitor 2-[4-[(4,6-dimethoxynaphthalen-2-yl)sulf... 3 16
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-07... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00425976 CHEMBL79267 Bioactive SureCN7253721
CFAMM00425990 CHEMBL311266 Bioactive SureCN7251321
CFAMM00425975 CHEMBL312100 Bioactive SureCN6290451
CFAMM00425968 CHEMBL315114 Bioactive SureCN6291161
CFAMM00425982 CHEMBL402745 Bioactive (2S)-2-[[4-(4-methoxyphenyl)phenyl]sulfonylamino]-2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
CFAMM00425995 CHEMBL82169 Bioactive SureCN7249879
CFAMM00425988 CHEMBL468101 Bioactive (2R)-2-[[4-(4-ethoxyphenyl)phenyl]sulfonylamino]-2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
CFAMM00425973 CHEMBL83282 Bioactive SureCN7255895
CFAMM00425987 CHEMBL253680 Bioactive (2R)-2-[[4-(4-methoxyphenyl)phenyl]sulfonylamino]-2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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