CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14072
Family Name Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00426035 Functional Category Bioactive
Superfamily Coagulation factor X and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 289

Cousin Family NamesSeedsMembers
Coagulation factor X inhibitor SureCN3834625 family 3 2
Coagulation factor X inhibitor 1-(6-chloronaphthalen-2-yl)sulf... 12 13
Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[1-(ethyl... 27 1
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 16 5
Melanocortin receptor 4 and Melanocortin receptor 5 ligand 3-[... 18 26
C-C chemokine receptor type 5 ligand AGN-PC-075XPW family 3 3
Coagulation factor X and Prothrombin inhibitor SureCN14502287 ... 16 5
Coagulation factor X inhibitor SureCN14490781 family 15 0
Coagulation factor X inhibitor SureCN4855529 family 6 0
Coagulation factor X inhibitor SureCN4463987 family 5 0
Cathepsin K inhibitor SureCN4163958 family 3 0


External ID

Functional Category

Molecule Name

CFAMM00426038 CHEMBL595707 Bioactive 6-chloro-N-[(3S)-1-[4-[1-(dimethylamino)ethyl]-2-fluorophenyl]-2-oxopyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
CFAMM00426036 CHEMBL595475 Bioactive 2vh6
CFAMM00426035 CHEMBL253942 Bioactive (E)-2-(5-chlorothiophen-2-yl)-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00426041 CHEMBL402359 Bioactive (E)-2-(4-chlorophenyl)-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide
CFAMM00426040 CHEMBL402064 Bioactive 5-chloro-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopiperidin-3-yl]thiophene-2-sulfonamide
CFAMM00426039 CHEMBL439418 Bioactive (E)-2-(6-chloro-1-benzothiophen-2-yl)-N-[1-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-2-oxopyrrolidin-3-yl]ethenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



42751 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543