CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14078
Family Name Kappa-type opioid receptor ligand AGN-PC-077Q4Y family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00426077 Functional Category Bioactive
Superfamily D(2) dopamine receptor and D(3) dopamine receptor Binder Superfamily 19
Class Class 2396

Cousin Family NamesSeedsMembers
Dopamine receptor Ligand Domperidone Family 2 21
Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family 1 21
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Histamine H3 receptor Ligand VUF-10214 Family 3 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 1
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
C-C chemokine receptor type 5 ligand AC1MHYGF family 3 2
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
Substance-P receptor and Mu-type opioid receptor ligand ethyl ... 1 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 6,7-dichlo... 2 0
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
Urotensin-2 receptor and Kappa-type opioid receptor ligand Sur... 2 0
Somatostatin receptor type 1 ligand AGN-PC-078XL4 family 2 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 2 1
Chymase and Chymotrypsinogen A inhibitor 3-(4-chlorophenyl)sul... 3 6
Bcl-2-related protein A1 and Microtubule-associated protein ta... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426071 CHEMBL254154 Bioactive 2-(3,4-dichloro-N-methylanilino)-1-[2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethanone
CFAMM00426070 CHEMBL526933 Bioactive AGN-PC-077Q7W
CFAMM00426077 CHEMBL502267 Bioactive AGN-PC-077Q4Y
CFAMM00426081 CHEMBL524367 Bioactive AGN-PC-077Q5O
CFAMM00426073 CHEMBL500407 Bioactive AGN-PC-077Q4Z

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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