CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14080
Family Name C-X-C chemokine receptor type 2 ligand 3-[[2-[[(1R)-1-(3-fluoro-5-methylphenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide family
No. of Seeds 14 No. of Other Members 0
Family Centroid CFAMM00426092 Functional Category Bioactive
Superfamily Dihydroorotate dehydrogenase Inhibitor Antimycin A Superfamily
Class Class 517

Cousin Family NamesSeedsMembers
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
Dihydroorotate dehydrogenase Inhibitor Antimycin A Family 1 0
Transient receptor potential cation channel subfamily V member... 2 29
C-X-C chemokine receptor type 2 ligand 3-[[3,4-dioxo-2-(pentan... 6 6
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 9 4
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 1 1
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 3 7
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 2 2
N-[3-[(E)-3-(dimethylamino)prop-2-enoyl]-4-hydroxyphenyl]aceta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426085 CHEMBL560089 Bioactive 5-cyano-3-[[3,4-dioxo-2-[[(1R)-1-phenylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426091 CHEMBL254176 Bioactive 3-[[2-[[(1R)-1-(3-cyano-5-methylphenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426090 CHEMBL404074 Bioactive 3-[[2-[[(1R)-1-(3-cyano-5-fluorophenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426096 CHEMBL404918 Bioactive 3-[[2-[[(1R)-1-(3,5-difluorophenyl)-2-methylpropyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426089 CHEMBL254776 Bioactive 3-[[2-[[(R)-cyclopropyl-(3,5-difluorophenyl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426095 CHEMBL254980 Bioactive 3-[[2-[[(1R)-1-[3-fluoro-5-(trifluoromethyl)phenyl]propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426088 CHEMBL254775 Bioactive 3-[[2-[[(1R)-1-(3,5-difluorophenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426094 CHEMBL254982 Bioactive 2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-2-methyl-1-[3-methyl-5-(trifluoromethyl)phenyl]propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
CFAMM00426087 CHEMBL557466 Bioactive 6-bromo-3-[[3,4-dioxo-2-[[(1R)-1-phenylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426093 CHEMBL254175 Bioactive 3-[[2-[[(1R)-1-(3-fluoro-5-methylphenyl)-2-methylpropyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426086 CHEMBL254570 Bioactive 3-[[2-[1-(4-fluoro-3-methylphenyl)propylamino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00426092 CHEMBL254174 Bioactive 3-[[2-[[(1R)-1-(3-fluoro-5-methylphenyl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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