CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14083
Family Name Prothrombin inhibitor 2-[6-cyano-3-[[2,2-difluoro-2-(3-methylpyridin-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00426127 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 Ligand AZD2207 Superfamily
Class Class 1006

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Amg 423 family 7 47
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Prothrombin inhibitor 2-[6-chloro-3-[(2,2-difluoro-2-pyridin-2... 4 3
Prothrombin inhibitor N-[(6-amino-2-methylpyridin-3-yl)methyl]... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426127 CHEMBL254785 Bioactive 2-[6-cyano-3-[[2,2-difluoro-2-(3-methylpyridin-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426126 CHEMBL254759 Bioactive 2-[3-[[2-(5-chloro-1-oxidopyridin-1-ium-2-yl)-2,2-difluoroethyl]amino]-6-cyano-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426125 CHEMBL401655 Bioactive 2-[6-cyano-3-[[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426130 CHEMBL258225 Bioactive N-[2-[carbamimidoyl(methyl)amino]oxyethyl]-2-[6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl]acetamide
CFAMM00426124 CHEMBL402758 Bioactive 2-[6-cyano-3-[[2,2-difluoro-2-(6-methylpyridin-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426123 CHEMBL254557 Bioactive 2-[3-[[2-(5-chloropyridin-2-yl)-2,2-difluoroethyl]amino]-6-cyano-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426129 CHEMBL254786 Bioactive 2-[6-cyano-3-[[2,2-difluoro-2-(4-methylpyridin-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426122 CHEMBL257543 Bioactive 2-[6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426128 CHEMBL254353 Bioactive 2-[6-cyano-2-fluoro-3-(quinolin-8-ylmethylamino)phenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide
CFAMM00426121 CHEMBL254784 Bioactive 2-[6-cyano-3-[[2,2-difluoro-2-(5-methylpyridin-2-yl)ethyl]amino]-2-fluorophenyl]-N-[2-(diaminomethylideneamino)oxyethyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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