CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14090
Family Name High affinity nerve growth factor receptor ligand CHEMBL254555 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00426189 Functional Category Bioactive
Superfamily Vascular endothelial growth factor receptor 2 Ligand Isoindolinone Urea Derivative Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Serine/threonine-protein kinase Chk1 Inhibitor BIS-IMIDE A Family 1 3
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
MAP kinase-activated protein kinase 2 and Mitogen-activated pr... 5 2
Thyroid hormone receptor beta and Microtubule-associated prote... 1 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 4 2
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426190 CHEMBL427901 Bioactive CHEMBL427901
CFAMM00426189 CHEMBL254555 Bioactive CHEMBL254555

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27284 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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