CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14097
Family Name Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyrrolidin-1-ylsulfonylbenzamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00426203 Functional Category Bioactive
Superfamily Type-1 angiotensin II receptor and Cannabinoid receptor 2 Binder Superfamily
Class Class 2586

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
DNA Binder Procarbazine Family 8 358
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Bavisant family 9 65
Chloride channel protein 2 Ligand Acid-activated Omeprazole Fa... 1 1
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Saccha... 2 13
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 5
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
Type-1 angiotensin II receptor ligand AGN-PC-04X45B family 9 12
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 1
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Type-1 angiotensin II receptor ligand AGN-PC-09QIDT family 2 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-met... 8 13
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Cathepsin K and Cathepsin L1 inhibitor N-[1-(cyanomethylcarbam... 2 0
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN32339... 2 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Bifunctional epoxide hydrolase 2 inhibitor N-(2-chlorophenyl)-... 2 1
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Neutrophil elastase inhibitor diethyl (1,1,3-trioxo-4-propan-2... 2 0
5-hydroxytryptamine receptor 1A and Alpha-2B adrenergic recept... 2 2
Amine oxidase [flavin-containing] A inhibitor N,7-dimethyl-9,1... 3 5
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Cannabinoid receptor 1 ligand 1-[4-[3-cyclopropyl-5-(trifluoro... 4 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Lethal(3)malignant brain tumor-like protein 3 and Lethal(3)mal... 1 0
Secreted frizzled-related protein 1 and Proto-oncogene Wnt-3 i... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426203 CHEMBL254730 Bioactive N-cyclohexyl-4-propan-2-yl-3-pyrrolidin-1-ylsulfonylbenzamide
CFAMM00426205 CHEMBL404647 Bioactive N-[(1S)-1-cyclohexylethyl]-4-methyl-3-piperidin-1-ylsulfonylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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