CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14110
Family Name Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibitor SureCN6595336 family
No. of Seeds 10 No. of Other Members 9
Family Centroid CFAMM00426275 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Binder Superfamily 2
Class Class 827

Cousin Family NamesSeedsMembers
Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
Cyclin-dependent kinase 2 Inhibitor N-(5-cyclopropyl-1h-pyrazo... 6 62
Glycogen synthase kinase-3 beta Inhibitor N-(6-(pyridin-4-yl)-... 4 23
Aurora kinase B and Aurora kinase C Inhibitor PHA-680632 Family 5 72
Glycogen synthase kinase-3 beta Inhibitor N-(6-chloro-5-p-toly... 5 9
Glycogen synthase kinase-3 beta Inhibitor (e)-n-(6-(prop-1-eny... 3 0
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 2 6
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 4 4
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(6-ph... 2 0
Neuropeptide Y receptor type 5 ligand 3-[3-[2-[[5-(4-chlorophe... 1 0
Aurora kinase A and Tyrosine-protein kinase SYK inhibitor AGN-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426272 CHEMBL402370 Bioactive SureCN6596290
CFAMM00426265 CHEMBL402157 Bioactive SureCN6596436
CFAMM00426264 CHEMBL404504 Bioactive SureCN6594677
CFAMM00426257 CHEMBL255262 Bioactive N-[5-(1,1-dioxo-1,2-thiazolidin-2-yl)-1H-indazol-3-yl]-2-(3-fluorophenyl)acetamide
CFAMM00426270 CHEMBL415789 Bioactive SureCN6596475
CFAMM00426263 CHEMBL254979 Bioactive SureCN6592978
CFAMM00426275 CHEMBL256558 Bioactive SureCN6595336
CFAMM00426268 CHEMBL257831 Bioactive 2-[4-(dimethylamino)phenyl]-N-[5-(1,1-dioxo-1,2-thiazolidin-2-yl)-1H-indazol-3-yl]acetamide
CFAMM00426261 CHEMBL402158 Bioactive SureCN6597272
CFAMM00426274 CHEMBL403605 Bioactive SureCN6593041

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27761 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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