CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14112
Family Name Arachidonate 5-lipoxygenase-activating protein inhibitor methyl 2-[2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethoxy)phenoxy]acetate family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00426282 Functional Category Bioactive
Superfamily Squalene synthase Inhibitor ER-119884 Superfamily
Class Class 1076

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Arachidonate 5-lipoxygenase-activating protein inhibitor 5-[2-... 7 1
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[2... 4 4
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426278 CHEMBL404266 Bioactive methyl 2-[2-(3-phenyl-3-bicyclo[2.2.1]heptanyl)-4-(quinolin-2-ylmethoxy)phenoxy]acetate
CFAMM00426282 CHEMBL255013 Bioactive methyl 2-[2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethoxy)phenoxy]acetate
CFAMM00426281 CHEMBL255228 Bioactive methyl 2-[2-(1-phenylcyclohexyl)-4-(quinolin-2-ylmethoxy)phenoxy]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27624 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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