CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14118
Family Name Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate family
No. of Seeds 6 No. of Other Members 11
Family Centroid CFAMM00426329 Functional Category Bioactive
Superfamily Transporter and Sodium-dependent serotonin transporter Binder Superfamily 3
Class Class 961

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Pitolisant family 4 24
Type-1 angiotensin II receptor Ligand RTI-76 Family 3 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 6
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sodium-dependent dopamine transporter and Transporter inhibito... 5 1
Sodium-dependent dopamine transporter and Transporter inhibito... 4 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 42
Sodium-dependent dopamine transporter and Transporter inhibito... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 8 6
Sodium-dependent serotonin transporter inhibitor CHEMBL265808 ... 1 0
Sodium-dependent dopamine transporter inhibitor (1R)-1-[(3S,4S... 1 1
Sodium-dependent serotonin transporter and Transporter inhibit... 4 2
Transporter and Sodium-dependent serotonin transporter inhibit... 4 0
Free fatty acid receptor 1 ligand (3R,4R)-3-(3,4-dichloropheny... 1 0
Sodium-dependent dopamine transporter inhibitor 2-(4-aminophen... 5 0
Sigma non-opioid intracellular receptor 1 and Muscarinic acety... 2 3
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 4
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
Transporter and Sodium-dependent dopamine transporter inhibito... 2 1
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 8 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Sigma non-opioid intracellular receptor 1 and Muscarinic acety... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426316 CHEMBL417960 Bioactive CHEMBL417960
CFAMM00426329 CHEMBL330651 Bioactive ethyl (3S,4S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00426320 CHEMBL318184 Bioactive 2-phenylethyl (3S,4S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
CFAMM00426319 CHEMBL420084 Bioactive propan-2-yl (3S,4S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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