CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14121
Family Name Serine/threonine-protein kinase Chk1 inhibitor 2,3-dimethoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one family
No. of Seeds 15 No. of Other Members 3
Family Centroid CFAMM00426345 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 1 Binder Superfamily
Class Class 1583

Cousin Family NamesSeedsMembers
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
5-hydroxytryptamine receptor 1B ligand SureCN5352760 family 2 5
Serine/threonine-protein kinase Chk1 inhibitor 9-(4-amino-3-me... 3 7
Serine/threonine-protein kinase Chk1 inhibitor 2-[9-(4-amino-3... 5 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN4849127 f... 4 1
Vascular endothelial growth factor receptor 2 ligand CHEMBL197... 1 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4856064 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426344 CHEMBL403192 Bioactive SureCN4855525
CFAMM00426337 CHEMBL404152 Bioactive 3-methoxy-2-[2-(2-methoxyethoxy)ethoxy]-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426350 CHEMBL272347 Bioactive 3-methoxy-9-(3-methoxy-4-nitrophenyl)-2-(oxan-2-ylmethoxy)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426343 CHEMBL257067 Bioactive 2-(2-hydroxyethyl)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426342 CHEMBL256193 Bioactive 2-(4-hydroxybutoxy)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426348 CHEMBL255183 Bioactive 2-(3-hydroxypropyl)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426341 CHEMBL256192 Bioactive 2-(3-aminopropoxy)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426354 CHEMBL404479 Bioactive 2-(3-hydroxy-3-methylbutyl)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426347 CHEMBL411098 Bioactive 3-methoxy-9-(3-methoxy-4-nitrophenyl)-2-(2-morpholin-4-ylethoxy)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426353 CHEMBL410195 Bioactive 2-hydroxy-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426346 CHEMBL270181 Bioactive 2-(2-hydroxyethoxy)-3-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426339 CHEMBL270417 Bioactive 3-(3-hydroxypropyl)-2-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426352 CHEMBL272711 Bioactive 3-[3-methoxy-9-(3-methoxy-4-nitrophenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-2-yl]-N,N-dimethylpropanamide
CFAMM00426345 CHEMBL404189 Bioactive 2,3-dimethoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
CFAMM00426338 CHEMBL257317 Bioactive 3-ethyl-2-methoxy-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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