CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14136
Family Name Mitogen-activated protein kinase 14 inhibitor (2R)-2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]propanamide family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00426468 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily 7
Class Class 4218

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Mitogen-activated protein kinase 14 inhibitor AGN-PC-044QVV fa... 4 2
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloropheny... 3 0
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloropheny... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426471 CHEMBL409901 Bioactive (2S)-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]pyrrolidine-2-carboxamide
CFAMM00426464 CHEMBL270611 Bioactive 1-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]cyclopropane-1-carboxamide
CFAMM00426470 CHEMBL257697 Bioactive 2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]-3-hydroxypropanamide
CFAMM00426463 CHEMBL256421 Bioactive (2R)-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]pyrrolidine-2-carboxamide
CFAMM00426469 CHEMBL270004 Bioactive 2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]-2-methylpropanamide
CFAMM00426468 CHEMBL255403 Bioactive (2R)-2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]propanamide
CFAMM00426467 CHEMBL437024 Bioactive 2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]acetamide
CFAMM00426466 CHEMBL403389 Bioactive 3-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]propanamide
CFAMM00426465 CHEMBL269792 Bioactive (2S)-2-amino-N-[2-[5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-2-oxoquinolin-7-yl]oxyethyl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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