CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14138
Family Name Macrophage colony-stimulating factor 1 receptor ligand 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-piperidin-4-ylphenyl]furan-2-carboxamide family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00426481 Functional Category Bioactive
Superfamily Macrophage colony-stimulating factor 1 receptor and Menin Binder Superfamily
Class Class 2780

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Phospholipase D1 and Phospholipase D2 inhibitor 4,5-dibromo-N-... 1 3
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 6 1
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Oxytocin receptor and Vasopressin V1a receptor ligand N-[[5-[4... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 1
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1971... 1 1


External ID

Functional Category

Molecule Name

CFAMM00426480 CHEMBL402908 Bioactive 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-(3-morpholin-4-ylprop-1-ynyl)phenyl]furan-2-carboxamide
CFAMM00426479 CHEMBL261699 Bioactive (E)-3-[4-[(5-cyanofuran-2-carbonyl)amino]-3-(4-methylpiperidin-1-yl)phenyl]prop-2-enoic acid
CFAMM00426478 CHEMBL257620 Bioactive N-[4-(1-acetylpiperidin-4-yl)-2-(4-methylpiperidin-1-yl)phenyl]-5-cyanofuran-2-carboxamide
CFAMM00426483 CHEMBL255443 Bioactive 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-(1,2,3,6-tetrahydropyridin-4-yl)phenyl]furan-2-carboxamide
CFAMM00426481 CHEMBL438533 Bioactive 5-cyano-N-[2-(4-methylpiperidin-1-yl)-4-piperidin-4-ylphenyl]furan-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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