CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1414
Family Name Type-1 angiotensin II receptor ligand AGN-PC-04X45B family
No. of Seeds 9 No. of Other Members 12
Family Centroid CFAMM00323147 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 3
Class Class 745

Cousin Family NamesSeedsMembers
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Angiotensin type II receptor ligand butyl N-[5-(2-methylpropyl... 1 3
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 8 6
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
Carbonic anhydrase 2 inhibitor AGN-PC-07BZZJ family 3 0
Angiotensin type II receptor ligand butyl N-[5-(2-methylpropyl... 1 1


External ID

Functional Category

Molecule Name

CFAMM00323151 CHEMBL246255 Bioactive AGN-PC-00A44F
CFAMM00323157 CHEMBL481089 Bioactive AGN-PC-078Z2Y
CFAMM00323150 CHEMBL1164870 Bioactive butyl N-[5-(2-methylpropyl)-3-[4-[(2-oxopyrrolidin-1-yl)methyl]phenyl]thiophen-2-yl]sulfonylcarbamate
CFAMM00323143 CHEMBL239393 Bioactive butyl N-[3-[4-[2-(dimethylamino)-2-oxoethyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate
CFAMM00323142 CHEMBL480906 Bioactive AGN-PC-04X45C
CFAMM00323141 CHEMBL517685 Bioactive AGN-PC-078Z4M
CFAMM00323147 CHEMBL521093 Bioactive AGN-PC-04X45B
CFAMM00323140 CHEMBL520421 Bioactive AGN-PC-078Z3U
CFAMM00323146 CHEMBL479399 Bioactive AGN-PC-078Z4N

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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