CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14153
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand N-[2-(5-methylfuran-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]-2-phenoxyacetamide family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00426653 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Adenosine receptor A1 Binder Superfamily 5
Class Class 2137

Cousin Family NamesSeedsMembers
Prelamin-A/C and Ferritin light chain inhibitor F2515-0416 family 2 4
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 1 14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Serine/threonine-protein kinase Chk1 inhibitor 2-(5-methoxy-3-... 4 5
Adenosine receptor A2a ligand 8-(furan-2-yl)-3-[2-[4-(1,3-thia... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
E-selectin and Intercellular adhesion molecule 1 inhibitor 4-(... 2 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M5I2 fa... 1 3


External ID

Functional Category

Molecule Name

CFAMM00426653 CHEMBL255649 Bioactive N-[2-(5-methylfuran-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]-2-phenoxyacetamide
CFAMM00426659 CHEMBL409700 Bioactive 2-(4-methoxyphenyl)-N-[2-(5-methylfuran-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide
CFAMM00426656 CHEMBL255860 Bioactive 2-(3-cyanophenoxy)-N-[2-(5-methylfuran-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide
CFAMM00426655 CHEMBL404739 Bioactive 2-(2-fluorophenoxy)-N-[2-(5-methylfuran-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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