CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14157
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-cyanophenoxy)-N-[2-pyridin-2-yl-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00426660 Functional Category Bioactive
Superfamily Glucokinase and cAMP Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Multiple kinase Inhibitor MGCD265 Family 19 71
Hydroxycarboxylic acid receptor 2 Ligand MBX-2982 Family 1 1
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Aurora kinase A inhibitor SureCN208325 family 1 5
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 1 14
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 7 7
LIM domain kinase 2 and LIM domain kinase 1 inhibitor N-[5-[6-... 1 22
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Leukotriene A-4 hydrolase inhibitor 1-[1-[[4-([1,3]thiazolo[4,... 9 13
Leukotriene A-4 hydrolase and Potassium voltage-gated channel ... 5 0
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Serine/threonine-protein kinase Chk1 inhibitor 2-(5-methoxy-3-... 4 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13 1
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Adenosine receptor A2a and Adenosine receptor A1 ligand N-[2-(... 5 6
Hepatocyte growth factor receptor ligand AGN-PC-077PZW family 1 0
Rho-associated protein kinase 2 and 3-hydroxyacyl-CoA dehydrog... 1 0
Serine/threonine-protein kinase PLK1 inhibitor SureCN2523858 f... 4 2
Prelamin-A/C and Ferritin light chain inhibitor F2515-0224 family 1 0
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 3 5
Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2... 1 8
Cysteinyl leukotriene receptor 1 and Platelet-activating facto... 1 1
Nuclear receptor ROR-gamma and Neuropeptide S receptor ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426697 CHEMBL256382 Bioactive 2-(4-methoxyphenyl)-N-[2-pyridin-2-yl-6-(1,3-thiazol-2-yl)pyrimidin-4-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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