CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1417
Family Name Pol polyprotein inhibitor 3-[[(4R,5R,6R)-6-[2-(4-fluorophenyl)ethyl]-4-[(4-fluorophenyl)methyl]-5-hydroxy-3-[[3-[(E)-N'-hydroxycarbamimidoyl]phenyl]methyl]-2-oxo-1,3-diazinan-1-yl]methyl]-N'-hydroxybenzenecarboximidamide family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00323167 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 13
Class Class 3367

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Pol polyprotein inhibitor Dmp 323 family 11 44
Pol polyprotein inhibitor (4R,5R,6S,7R)-1,3,4,7-tetrabenzyl-5,... 12 29
Pol polyprotein inhibitor 3-[(4R,5R,6R)-3-[3-[(E)-1-amino-2-hy... 2 4
Pol polyprotein inhibitor AC1LAMTL family 11 15
Pol polyprotein inhibitor (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bi... 3 2
Pol polyprotein inhibitor Cyclic Urea 64 family 12 1
Pol polyprotein inhibitor AC1LAMTC family 6 0
Pol polyprotein inhibitor AC1LAMVF family 2 0
Pol polyprotein inhibitor (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihyd... 6 0
Pol polyprotein inhibitor AC1LADP4 family 2 0
Pol polyprotein inhibitor AC1LAH82 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00323166 CHEMBL416964 Bioactive AC1NS2LF
CFAMM00323172 CHEMBL36900 Bioactive 3-[[(4R,5R,6R)-6-[2-(3,4-difluorophenyl)ethyl]-4-[(3,4-difluorophenyl)methyl]-5-hydroxy-3-[[3-[(Z)-N'-hydroxycarbamimidoyl]phenyl]methyl]-2-oxo-1,3-diazinan-1-yl]methyl]-N'-hydroxybenzenecarboximidamide
CFAMM00323171 CHEMBL366576 Bioactive 5-[[(4R,5R,6R)-4-benzyl-3-[[4-fluoro-3-[(Z)-N'-hydroxycarbamimidoyl]phenyl]methyl]-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]methyl]-2-fluoro-N'-hydroxybenzenecarboximidamide
CFAMM00323176 CHEMBL286159 Bioactive AC1NS2LC
CFAMM00323168 CHEMBL287923 Bioactive AC1NS2LO
CFAMM00323174 CHEMBL284942 Bioactive AC1NS2K3
CFAMM00323167 CHEMBL116517 Bioactive 3-[[(4R,5R,6R)-6-[2-(4-fluorophenyl)ethyl]-4-[(4-fluorophenyl)methyl]-5-hydroxy-3-[[3-[(E)-N'-hydroxycarbamimidoyl]phenyl]methyl]-2-oxo-1,3-diazinan-1-yl]methyl]-N'-hydroxybenzenecarboximidamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543