CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14175
Family Name Gonadotropin-releasing hormone receptor ligand 5-(2-chloro-3-methoxyphenyl)-3-[(2S)-2-(cyclopentylamino)propyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00426804 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone receptor Binder Superfamily 5
Class Class 3124

Cousin Family NamesSeedsMembers
Elagolix family 43 98
Neutrophil elastase inhibitor benzyl 2-[2,4,8-trioxo-7-[2-oxo-... 2 2


External ID

Functional Category

Molecule Name

CFAMM00426805 CHEMBL401807 Bioactive 5-(2-chloro-3-methoxyphenyl)-3-[(2R)-2-(cyclopentylamino)butyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione
CFAMM00426804 CHEMBL256109 Bioactive 5-(2-chloro-3-methoxyphenyl)-3-[(2S)-2-(cyclopentylamino)propyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione
CFAMM00426803 CHEMBL404180 Bioactive 5-(2-chloro-3-methoxyphenyl)-3-[(2S)-2-(cyclopentylamino)butyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione
CFAMM00426802 CHEMBL556355 Bioactive 5-(2-chloro-3-methoxyphenyl)-3-[(2R)-2-(cyclopentylamino)-3-hydroxypropyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione;hydrochloride
CFAMM00426806 CHEMBL403234 Bioactive 5-(2-chloro-3-methoxyphenyl)-3-[(2R)-2-(cyclopentylamino)-3-hydroxypropyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methylpyrimidine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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