CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14177
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor 1-[4-(4-chloro-2-methylphenoxy)-6-methylpyridin-3-yl]-N,N-dimethylmethanamine family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00418416 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter Binder Superfamily 2
Class Class 873

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
Corticotropin-releasing factor receptor 1 Ligand Cp-316,311 Fa... 5 74
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Dihydroorotate dehydrogenase Inhibitor LY214352 Family 2 17
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Metabotropic glutamate receptor 5 Ligand 2-(3-chlorobenzyloxy)... 2 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 3 24
Glucagon receptor and Mitogen-activated protein kinase 14 liga... 6 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Prostaglandin D2 receptor 2 ligand 2-[4-chloro-2-[2-(4-propylp... 2 13
Metabotropic glutamate receptor 5 ligand 2-chloro-6-[(2-methyl... 1 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 7
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 1 1
Sodium-dependent serotonin transporter inhibitor SureCN5878703... 4 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 6
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 2 3
Enoyl-acyl-carrier protein reductase inhibitor Triclosan deriv... 3 0
Beta-lactamase and DNA polymerase beta inhibitor ZINC05065687 ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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