CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14179
Family Name C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 ligand (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-propan-2-yl-3-(4-pyrimidin-5-ylpiperidin-1-yl)cyclopentane-1-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00426826 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 1006

Cousin Family NamesSeedsMembers
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Substance-P receptor ligand (3R,4S)-N-[[3,5-bis(trifluoromethy... 3 7
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-(6-pyrrolid... 3 0
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 1 2
Melanin-concentrating hormone receptor 1 and Alpha-2A adrenerg... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426827 CHEMBL429849 Bioactive (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-(2-hydroxypropan-2-yl)-3-(4-pyrimidin-5-ylpiperidin-1-yl)cyclopentane-1-carboxamide
CFAMM00426826 CHEMBL256154 Bioactive (1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-propan-2-yl-3-(4-pyrimidin-5-ylpiperidin-1-yl)cyclopentane-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26223 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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