CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14183
Family Name C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl)-1-[4-[2-hydroxy-1-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00426855 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and C-C chemokine receptor type 3 Binder Superfamily
Class Class 3182

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Sertindole Family 3 173
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
ABC294640 family 5 75
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 2 4
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... 3 2
C-C chemokine receptor type 2 ligand SureCN5947024 family 11 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
C-C chemokine receptor type 2 ligand 3-[1-[1-[1-[(3,4-dichloro... 1 1
C-C chemokine receptor type 2 and Cytochrome P450 2D6 ligand (... 4 1
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 2
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426855 CHEMBL258205 Bioactive (E)-3-(3,4-dichlorophenyl)-1-[4-[2-hydroxy-1-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]prop-2-en-1-one
CFAMM00426854 CHEMBL256301 Bioactive N-[3-[1-[1-[1-[(E)-3-(3,4-dichlorophenyl)prop-2-enoyl]piperidin-4-yl]-2-hydroxyethyl]piperidin-4-yl]-1H-indol-5-yl]methanesulfonamide
CFAMM00426853 CHEMBL438353 Bioactive N-(3,4-dichlorophenyl)-4-[2-hydroxy-1-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]piperidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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