CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14186
Family Name Prothrombin inhibitor N-(2-aminoethyl)-2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetamide family
No. of Seeds 17 No. of Other Members 5
Family Centroid CFAMM00426891 Functional Category Bioactive
Superfamily Sodium- and Prothrombin Binder Superfamily
Class Class 930

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Plinabulin family 1 0
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Prothrombin inhibitor SureCN5855598 family 4 2
Prothrombin inhibitor SureCN5856722 family 3 16
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 16
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
Prothrombin and Trypsin-1 inhibitor N-[(6-amino-2-methylpyridi... 3 0
Prothrombin and Trypsin-1 inhibitor AGN-PC-073QCQ family 3 0
A disintegrin and metalloproteinase with thrombospondin motifs... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426893 CHEMBL409921 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-piperidin-1-ylacetamide
CFAMM00426873 CHEMBL271649 Bioactive N-(1-amino-2-methylpropan-2-yl)-2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetamide
CFAMM00426886 CHEMBL402724 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-(3-hydroxyazetidin-1-yl)acetamide
CFAMM00426885 CHEMBL270357 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-ethylacetamide
CFAMM00426878 CHEMBL257507 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-morpholin-4-ylacetamide
CFAMM00426891 CHEMBL270252 Bioactive N-(2-aminoethyl)-2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetamide
CFAMM00426884 CHEMBL401682 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-tert-butylacetamide
CFAMM00426877 CHEMBL402095 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-piperidin-3-ylacetamide
CFAMM00426890 CHEMBL258066 Bioactive N-(2-amino-2-methylpropyl)-2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetamide
CFAMM00426876 CHEMBL270650 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-(2,2,2-trifluoroethyl)acetamide
CFAMM00426889 CHEMBL271675 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-(2-hydroxyethyl)acetamide
CFAMM00426882 CHEMBL270861 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-(cyclopropylmethyl)acetamide
CFAMM00426888 CHEMBL270649 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-(2-methylbutan-2-yl)acetamide
CFAMM00426875 CHEMBL373260 Bioactive AGN-PC-00CS9L
CFAMM00426894 CHEMBL256450 Bioactive 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]-N-cyclopropylacetamide
CFAMM00426887 CHEMBL402854 Bioactive N-(3-aminocyclobutyl)-2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetamide
CFAMM00426880 CHEMBL258286 Bioactive tert-butyl 2-[5-[[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]methyl]-4-methylimidazol-1-yl]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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