CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14187
Family Name Coagulation factor X inhibitor SureCN4463987 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00426899 Functional Category Bioactive
Superfamily Coagulation factor X and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 3169

Cousin Family NamesSeedsMembers
Coagulation factor X inhibitor 1-(6-chloronaphthalen-2-yl)sulf... 12 13
Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[1-(ethyl... 27 1
Melanocortin receptor 4 and Melanocortin receptor 5 ligand AC1... 5 37
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 3 0
Coagulation factor X inhibitor (E)-2-(5-chlorothiophen-2-yl)-N... 6 1
B1 bradykinin receptor ligand 2-[(2R)-1-(3,4-dichlorophenyl)su... 1 0


External ID

Functional Category

Molecule Name

CFAMM00426899 CHEMBL256451 Bioactive SureCN4463987
CFAMM00426898 CHEMBL270565 Bioactive 2-[(6-chloronaphthalen-2-yl)sulfonyl-[1-[2-fluoro-4-(2-oxopiperidin-1-yl)phenyl]-2-oxopiperidin-3-yl]amino]-N-[2-(dimethylamino)ethyl]-N-methylacetamide
CFAMM00426897 CHEMBL271904 Bioactive 6-chloro-N-[1-[2-fluoro-4-(2-oxopyridin-1-yl)phenyl]-2-oxopiperidin-3-yl]naphthalene-2-sulfonamide
CFAMM00426896 CHEMBL257037 Bioactive 6-chloro-N-[1-[2-fluoro-4-(2-oxopiperidin-1-yl)phenyl]-2-oxopiperidin-3-yl]naphthalene-2-sulfonamide
CFAMM00426895 CHEMBL401958 Bioactive 2-[(6-chloronaphthalen-2-yl)sulfonyl-[(3S)-1-[2-fluoro-4-(2-oxopyridin-1-yl)phenyl]-2-oxopiperidin-3-yl]amino]-N-[2-(dimethylamino)ethyl]-N-methylacetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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