CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14189
Family Name D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A ligand N-[2-[(6-methoxy-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-4-(4-methoxyphenyl)butan-1-amine family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00184182 Functional Category Bioactive
Superfamily D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A ligand N-[2-[(6-methoxy-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-4-(4-methoxyphenyl)butan-1-amine Superfamily
Class Class 2531

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Serotonin re-uptake Inhibitor Paroxetine Family 6 19
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
D(3) dopamine receptor Ligand U-99194A Family 7 33
Acolbifene family 10 115
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 2
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 2 2
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 2
Alpha-1A adrenergic receptor and 5-hydroxytryptamine receptor ... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 7 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
5-hydroxytryptamine receptor 7 and Alpha-2C adrenergic recepto... 3 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 10 8
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
High affinity choline transporter 1 inhibitor 1-[4-(3,4,5-trim... 2 3
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Putative NP ZINC01322649 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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