CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14197
Family Name Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2,5-dioxo-1H-chromeno[3,4-f]quinoline-9-carboxylate family
No. of Seeds 2 No. of Other Members 57
Family Centroid CFAMM00426992 Functional Category Bioactive with Natural Product
Superfamily Androgen receptor Binder Superfamily 8
Class Class 1873

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 9 16
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Mineralocorticoid receptor and Androgen receptor Ligand LGD-55... 6 6
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 7
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
Androgen receptor ligand 9-ethoxy-10-methoxy-4-methyl-1H-chrom... 3 4
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 2
Progesterone receptor and Androgen receptor ligand (4R,5S)-5-(... 5 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Retinoic acid receptor RXR-gamma and Retinoic acid receptor RX... 3 36
Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransfer... 1 0
Cytochrome P450 2D6 inhibitor 2-[(3-butoxyphenoxy)methyl]-3-me... 1 0
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14
Tyrosine-protein kinase ABL1 inhibitor N-(4-bromophenyl)-2-(5-... 1 3
Malate dehydrogenase, mitochondrial and Lactate dehydrogenase ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00426992 CHEMBL256769 Bioactive trifluoromethyl 10-methoxy-4-methyl-2,5-dioxo-1H-chromeno[3,4-f]quinoline-9-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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