CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14198
Family Name Cannabinoid receptor 2 ligand 6-chloro-1-(cyclohexylmethyl)-2-[(4-ethoxyphenyl)methyl]-5-ethylsulfonylbenzimidazole family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00427031 Functional Category Bioactive
Superfamily Beta-lactamase and Cannabinoid receptor 2 Binder Superfamily
Class Class 4236

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 11 35
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 3
Prostaglandin G/H synthase 2 inhibitor SureCN6777506 family 1 2
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 13 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4


External ID

Functional Category

Molecule Name

CFAMM00427031 CHEMBL256993 Bioactive 6-chloro-1-(cyclohexylmethyl)-2-[(4-ethoxyphenyl)methyl]-5-ethylsulfonylbenzimidazole
CFAMM00427030 CHEMBL256992 Bioactive 6-chloro-1-(cyclohexylmethyl)-2-[(4-ethoxyphenyl)methyl]-5-ethylsulfinylbenzimidazole
CFAMM00427029 CHEMBL256781 Bioactive 2-[(4-ethoxyphenyl)methyl]-5-ethylsulfonyl-1-(oxan-4-ylmethyl)benzimidazole
CFAMM00427028 CHEMBL403045 Bioactive 6-chloro-2-[(4-ethoxyphenyl)methyl]-5-ethylsulfanyl-1-(oxan-4-ylmethyl)benzimidazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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