CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14201
Family Name Metabotropic glutamate receptor 2 ligand 8-[2-(4-fluorophenyl)ethynyl]-4-[3-(triazol-1-yl)phenyl]-1,3-dihydro-1,5-benzodiazepin-2-one family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00427050 Functional Category Bioactive
Superfamily Cathepsin S and Histone deacetylase 6 Binder Superfamily
Class Class 3219

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelegatran Family 8 157
Prothrombin Inhibitor Dabigatran Family 7 182
D(3) dopamine receptor Ligand SB-277011 Family 13 178
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-9... 3 13
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... 20 37
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 3
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 3 3
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 5 3
Metabotropic glutamate receptor 2 ligand AGN-PC-09QHIM family 2 0
Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family 2 0
Metabotropic glutamate receptor 2 ligand AGN-PC-01XRTW family 1 0
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 7 0
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Gonadotropin-releasing hormone receptor ligand 1-[2-(3,5-dimet... 2 0
Steroid hormone receptor ERR1 ligand methyl 3-[4-(2-aminobenzo... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427052 CHEMBL408229 Bioactive AGN-PC-01XRW4
CFAMM00427050 CHEMBL256812 Bioactive 8-[2-(4-fluorophenyl)ethynyl]-4-[3-(triazol-1-yl)phenyl]-1,3-dihydro-1,5-benzodiazepin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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