CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14209
Family Name Urotensin-2 receptor and Cytochrome P450 3A4 ligand 6,7-dichloro-1-[2-[2-(morpholin-4-ylmethyl)-3-phenylpiperidin-1-yl]-2-oxoethyl]quinoxalin-2-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00427070 Functional Category Bioactive
Superfamily Urotensin-2 receptor and Cytochrome P450 3A4 Binder Superfamily 2
Class Class 3297

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
C-C chemokine receptor type 5 ligand AC1MHYGF family 3 2
Kappa-type opioid receptor ligand AGN-PC-077Q4Y family 5 9
Urotensin-2 receptor and Cytochrome P450 2D6 ligand 2-[3,4-dic... 2 3
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Urotensin-2 receptor and Kappa-type opioid receptor ligand Sur... 2 0
Somatostatin receptor type 1 ligand AGN-PC-078XL4 family 2 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0


External ID

Functional Category

Molecule Name

CFAMM00427089 CHEMBL256989 Bioactive 6,7-dichloro-1-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]quinoxalin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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