CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14214
Family Name C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00427121 Functional Category Bioactive
Superfamily C-C chemokine receptor type 2 and Collagenase 3 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Penicillin binding protein Inhibitor Cefadroxil Family 5 17
Thymopentin family 20 133
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Histamine H3 receptor Ligand A-317920 Family 9 240
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Scytalone dehydratase Inhibitor 5-fluoro-2-hydroxy-n-isopropyl... 3 14
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 4-hy... 2 13
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
D(2) dopamine receptor Ligand Epidepride Family 31 66
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 9
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Delta-type opioid receptor and Kappa-type opioid receptor liga... 15 6
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 4 15
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Coagulation factor X inhibitor 3-[4-[[(E)-3-[3-(diaminomethyli... 4 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 7
Dipeptidyl peptidase 4 inhibitor SureCN5777647 family 1 0
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 5 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Beta-lactamase inhibitor sodium;(1R,5S)-4-[2-amino-2-(4-hydrox... 1 0
Dipeptidyl peptidase 4 inhibitor ethyl 2-[[4-[[4-[(2-ethoxy-2-... 7 0
C-C chemokine receptor type 3 ligand SureCN3932025 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427121 CHEMBL257064 Bioactive 2-amino-N-[2-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
CFAMM00427125 CHEMBL402723 Bioactive N-[2-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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