CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14218
Family Name Beta-3 adrenergic receptor and Beta-1 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]benzoic acid family
No. of Seeds 9 No. of Other Members 14
Family Centroid CFAMM00426867 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-3 adrenergic receptor Binder Superfamily 3
Class Class 4644

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 1 5
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 15 13
Beta-3 adrenergic receptor ligand SureCN4584432 family 5 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 7 1
Beta-3 adrenergic receptor ligand SureCN4583819 family 5 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 0
Extracellular calcium-sensing receptor ligand SureCN4609584 fa... 7 8


External ID

Functional Category

Molecule Name

CFAMM00427157 CHEMBL411028 Bioactive 4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-(2-methylpropyl)benzoic acid
CFAMM00427163 CHEMBL408145 Bioactive 4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-3-fluorobenzoic acid
CFAMM00427154 CHEMBL271367 Bioactive 4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-fluorobenzoic acid
CFAMM00427159 CHEMBL257106 Bioactive 4-[2-chloro-4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]benzoic acid
CFAMM00427165 CHEMBL257297 Bioactive 3-chloro-4-[4-[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]benzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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