CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14219
Family Name Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,3-benzoxazol-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00427174 Functional Category Bioactive
Superfamily Cruzipain and Prelamin-A/C Binder Superfamily 18
Class Class 4262

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
D(4) dopamine receptor ligand AGN-PC-004XJQ family 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(4-... 3 5
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
C-C chemokine receptor type 1 ligand SureCN3164653 family 2 1
Translocator protein inhibitor AGN-PC-00CH84 family 3 0
Translocator protein inhibitor [11C]DAA1106 family 15 2
Translocator protein inhibitor N-methyl-2-[2-oxo-5-[4-(trifluo... 9 3
Translocator protein inhibitor 2-(5-chloro-2-oxo-1,3-benzoxazo... 1 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
Urotensin-2 receptor and Kappa-type opioid receptor ligand 6,7... 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
Acyl-CoA desaturase and Acyl-CoA desaturase 1 inhibitor SureCN... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 0
P2X purinoceptor 7 inhibitor SureCN3722920 family 4 0


External ID

Functional Category

Molecule Name

CFAMM00427174 CHEMBL257150 Bioactive 5-chloro-3-[2-oxo-2-[3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethyl]-1,3-benzoxazol-2-one
CFAMM00427173 CHEMBL473783 Bioactive AGN-PC-04XRFG

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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