CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14220
Family Name Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihydrochromeno[3,4-f]quinolin-2-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00427180 Functional Category Bioactive
Superfamily Androgen receptor and Melatonin receptor type 1B Binder Superfamily
Class Class 615

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 9 16
Mineralocorticoid receptor and Androgen receptor Ligand LGD-55... 6 6
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
Androgen receptor ligand (6R,7R)-6,7-diethyl-4-(trifluoromethy... 15 20
Androgen receptor ligand 9-ethoxy-10-methoxy-4-methyl-1H-chrom... 3 4
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
Glucocorticoid receptor and Progesterone receptor ligand SureC... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 2
Progesterone receptor and Androgen receptor ligand (4R,5S)-5-(... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427180 CHEMBL257151 Bioactive 10-(hydroxymethyl)-4-methyl-1,5-dihydrochromeno[3,4-f]quinolin-2-one
CFAMM00427178 CHEMBL450334 Bioactive 4-(trifluoromethyl)-1,6-dihydroisochromeno[3,4-f]quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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