CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14224
Family Name Mitogen-activated protein kinase 14 inhibitor 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxyquinolin-2-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00427196 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily 7
Class Class 4218

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 inhibitor AGN-PC-044QVV fa... 4 2
Mitogen-activated protein kinase 14 inhibitor (2R)-2-amino-N-[... 9 0
Mitogen-activated protein kinase 14 inhibitor 5-(2-chloropheny... 2 1


External ID

Functional Category

Molecule Name

CFAMM00427195 CHEMBL403925 Bioactive 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-methoxyquinolin-2-one
CFAMM00427194 CHEMBL271850 Bioactive 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-3,7-dihydroxyquinolin-2-one
CFAMM00427196 CHEMBL257236 Bioactive 5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydroxyquinolin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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