CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14230
Family Name Glucocorticoid receptor ligand 4-[[(4aS)-6-(4-tert-butylphenyl)sulfonyl-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-4a-yl]methyl]morpholine family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00427220 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 Inhibitor Celecoxib Superfamily
Class Class 428

Cousin Family NamesSeedsMembers
Glucocorticoid receptor ligand N-[(3S)-3-[1-(4-fluorophenyl)in... 11 24
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 35
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Glucocorticoid receptor ligand (4aR)-1-(4-fluorophenyl)-4a-(me... 18 2
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Glucocorticoid receptor ligand 6-benzyl-1-(4-fluorophenyl)-4a-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00427221 CHEMBL403966 Bioactive (4aR)-6-(4-tert-butylphenyl)sulfonyl-1-(4-fluorophenyl)-4a-(2-piperidin-1-ylethoxymethyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline
CFAMM00427220 CHEMBL270838 Bioactive 4-[[(4aS)-6-(4-tert-butylphenyl)sulfonyl-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-4a-yl]methyl]morpholine
CFAMM00427223 CHEMBL257461 Bioactive 4-[[(4aS)-6-(benzenesulfonyl)-1-(4-fluorophenyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-4a-yl]methyl]morpholine
CFAMM00427222 CHEMBL402351 Bioactive 4-[4-[[1-(4-fluorophenyl)-4a-[(4-fluorophenyl)methyl]-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-6-yl]sulfonyl]phenyl]morpholine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27163 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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